pentobarbital will lower the level or effect of verapamil by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.Keep track of Closely (2)pentobarbital will lower the level or result of suvorexant by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on. Potent CYP3A4 inducers may decrease suvorexant